miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts
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چکیده
منابع مشابه
miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts
Uncontrolled cell proliferation and cytoskeletal remodeling are responsible for tumor development and ultimately metastasis. A number of studies have implicated microRNAs in the regulation of cancer cell invasion and migration. Here, we show that miR-23b regulates focal adhesion, cell spreading, cell-cell junctions and the formation of lamellipodia in breast cancer (BC), implicating a central r...
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The James Buchanan Brady Urological Institute and Department of Urology; Johns Hopkins School of Medicine; Baltimore, MD USA; The James Buchanan Brady Urological Institute and Department of Oncology; Johns Hopkins School of Medicine; Baltimore, MD USA; The James Buchanan Brady Urological Institute and Department of Pharmacology and Molecular Science; Johns Hopkins School of Medicine; Baltimore;...
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Objective(s): To investigate the effect of miR-103 on the angiogenesis of ischemic stroke rats via targeting vascular endothelial growth factor (VEGF) at the molecular level. Materials and Methods: Rat models had received the middle cerebral artery occlusion (MCAO) or sham operation before grouping, and cell models of oxygen-glucose deprivation (OGD) were performed. FITC-dextran, matrigel, and ...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2013
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkt245